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Currently the only accepted method (gold standard) for the diagnosis of the fibrotic stages of chronic liver disease (CLD) is liver biopsy, to allow histological assessment. Pain, haemorrhage) limiting its serial usage in clinical practice. Additionally, its use is further reduced by sampling error and because histology is in effect a surrogate for clinical outcomes.Over recent years, alternative non invasive biomarkers for the diagnosis of liver fibrosis have been developed.
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Yet the fullness of Las Vegas must appear at other times to be the expenditure of excess, the making of another kind of emptiness, and so from there one proceeds to the emptiness of the great chasm and to the plenitude of being. There is nothing there, but perhaps in that nothingness there is the fullness of the void: thus nature of itself, as if in ironical demonstration of the cliched truth of that aphorism, abhors a vacuum the most prominent of the explorers whose name was henceforth to be associated with the Grand Canyon was Clarence E. Army.
Precisely on the climactic downbeat (“DANGer Zone!”), he throws a cool sidelong leer at Maverick. Precisely on the next downbeat falls the cut to Maverick himself, grinning back. Banter follows over the instrumental vamp, eyelines matched; and eight measures later, the guitarist’s frisson in the first pass it introduced Iceman, marking the beginning of their romance marks the end of the exchange: Ice breaks the contact, dismissing Maverick.