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The aim of this study was to compare a low cost, high throughput root phenotyping (HTP) technique in a controlled environment with field performance, using oilseed rape (OSR; Brassica napus) varieties.Methods. Primary root length (PRL), lateral root length and lateral root density (LRD) were measured on 14 d old seedlings of elite OSR varieties (n 14 32) using a pouch and wick TM HTP system (40 replicates). Six field exper iments were conducted using the same varieties at two UK sites each year for 3 years.

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In the majority of the measured parameters which showed a sex difference, maternal smoking reduced the magnitude of that difference. Maternal smoking also altered DNA methylation at the imprinted gene IGF2 and the glucocorticoid receptor (GR/NR3C1).Conclusions: Our unique data strengthen studies linking in utero exposures to altered DNA methylation by showing, for the first time, that such changes are present in fetal life and in a key metabolic target tissue, human fetal liver. Furthermore, these data propose a novel mechanism by which such changes are induced, namely through alterations in methyl donor availability and changes in 1 carbon metabolism..

Qu’on n’aura pas vu le soleil ni prononc la moindre parole. On pense enfin que c’tait pas vraiment la peine, et mme vraiment pas la peine, de se lever aujourd’hui : autant passer directement du lundi au mercredi. Ca aurait chang quoi ? Aujourd’hui, on n’aura servi rien, personne.

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To achieve this we used an analysis of the published literature, a study of illustrations of hominin evolution from 1925 onwards and an email survey of senior researchers in palaeoanthropology and related fields. We found that the term mosaic starts to be applied in palaeoanthropological thinking during the 1970 TMs due to the work of a number of researchers, including Karl Butzer and Glynn Isaac , with the earliest usage we have found of mosaic TM in specific reference to hominin habitats being by Adriaan Kortlandt (1972). While we observe a steady increase in the numbers of publications reporting mosaic palaeohabitats, in keeping with the growing interest and specialisation in various methods of palaeoenvironmental reconstruction, we also note that there is a lack of critical studies that define this habitat, or examine the temporal and spatial scales associated with it.

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